Recent studies on Helicobacter pylori and CagA seroprevalence in children are scarce. This study aimed to find H. pylori IgG and CagA IgG in asymptomatic Bulgarian children. H. pylori IgG and CagA IgG were detected through ELISA method. H. pylori IgG prevalence was 24.2% and CagA IgG were found in 40% of H. pylori IgG positive children. Both were significantly lower than recently found in Bulgarian adults ( p < 0.0001, and p = 0.014, respectively). H. pylori seroprevalence was lowest (13.5%) in 1–3 years old children. H. pylori infection and virulence in Bulgaria show a steady decline.
Key words: Helicobacter pylori , seroprevalence, CagA
Topic: MEDICINE