Comptes rendus de l’Acade'mie bulgare des Sciences, Vol 61, No3, pp.321-326

GLAUCINE RECOVERY AND CONCENTRATION APPLYING LIQUID MEMBRANE TECHNIQUE

Madlena Lazarova, Krasimir Dimitrov, Daniela Metcheva, Lubomir Boyadzhiev

ABSTRACT

Glaucine, an aporphine alkaloid with pronounced analgetic and antitusive effect was extracted and concentrated applying liquid membrane (pertraction) technique. Two organic solvents, chloroformand di-iso-propyl ether, were tested as potential membrane liquids varying the pH value of aqueous feed phase and the ether was chosen due to its much lower toxicity, lower solubility and better stripping results. The experiments were carried out in a laboratory rotating disc pertractor studying the effect of disc rotation velocity. It was shown that the alkaloid could be almost completely recovered and due to the difference between the pH-values and the volumes of feed and the stripping aqueous solutions, a considerable concentration of glaucine in the latter can be obtained.


Key words: glaucine, extraction, liquid membranes, pertraction, preconcentration

Topic: CHEMISTRY