Microbial Transformation of Lycorine by Talaromyces pinophilus Isolated from the Rhizosphere of Leucojum aestivum L.
DOI:
https://doi.org/10.7546/CRABS.2023.05.05Keywords:
lycorine, Leucojum aestivum L., Talaromyces pinophilus, microbial transformation, 2-oxolycorineAbstract
In the present study we report on the isolation of 12 strains of filamentous fungi from the rhizosphere of Leucojum aestivum L. (Amaryllidaceae). They were screened for ability to transform the Amaryllidaceae alkaloid lycorine. Gas chromatography-mass spectrometry was applied to analyze the samples. The Talaromyces pinophilus S120 strain was found to transform 19% of lycorine into its 2-oxo-derivative. To the best of our knowledge, this is the first report on transformation of lycorine by a filamentous fungus.
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