Nanofiltration as a Sustainable Tool for Concentrating Bioactive Compounds in Mavrud Red Wine

Authors

  • Madlena Lazarova Bulgarian Academy of Sciences
  • Maria Dencheva-Zarkova Bulgarian Academy of Sciences
  • Dragomir Yankov Bulgarian Academy of Sciences
  • Julia Genova Bulgarian Academy of Sciences

DOI:

https://doi.org/10.7546/CRABS.2026.04.03

Keywords:

red wine, nanofiltration, concentration, polyphenols, flavonoids, anthocyanins

Abstract

In the present study, nanofiltration for concentrating total polyphenols, flavonoids, and anthocyanins in Mavrud red wine was performed. The MaxiMem membrane filtration system, employing the Microdyn Nadir® NP030 P nanofiltration membrane, was utilized for this purpose. The effects of transmembrane pressure (20–50 bar) and flow rate (1.2–3 L min-1) on the contents of phenolics, flavonoids, and anthocyanins in the wine were evaluated. The radical scavenging capacity and total antioxidant activity of the wine and wine concentrates, were also assessed. All wine concentrates exhibited higher concentrations of bioactive compounds and antioxidant activity than the original wine. Overall best concentration results for the three groups of analyzed compounds were determined at 40 bar pressure and 1.2 L min-1 flow rate, showing values of 3925.0 mg GAE L-1, 1386.3 mg CE L-1, and 158.0 mg ME L-1. The highest antioxidant activity of 15.2 mmol TE L-1 was reached at 40 and 50 bar pressure and 1.2 L min-1 flow rate. The results indicate that nanofiltration is a sustainable tool for concentrating phenolics in red wine.

Author Biographies

Madlena Lazarova, Bulgarian Academy of Sciences

Mailing Address:
Institute of Chemical Engineering,
Bulgarian Academy of Sciences
Akad. G. Bonchev St, Bl. 103,
1113 Sofia, Bulgaria

E-mail: m.lazarova@iche.bas.bg

Maria Dencheva-Zarkova, Bulgarian Academy of Sciences

Mailing Address:
Georgi Nadjakov Institute of Solid State Physics,
Bulgarian Academy of Sciences,
72 Tsarigradsko Shosse Blvd,
1784 Sofia, Bulgaria

E-mail: biolayer@issp.bas.bg

Dragomir Yankov, Bulgarian Academy of Sciences

Mailing Address:
Institute of Chemical Engineering,
Bulgarian Academy of Sciences
Akad. G. Bonchev St, Bl. 103,
1113 Sofia, Bulgaria

E-mail: yanpe@bas.bg

Julia Genova, Bulgarian Academy of Sciences

Mailing Address:
Georgi Nadjakov Institute of Solid State Physics,
Bulgarian Academy of Sciences,
72 Tsarigradsko Shosse Blvd,
1784 Sofia, Bulgaria

E-mail: ulia@issp.bas.bg

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Published

27-04-2026

How to Cite

[1]
M. Lazarova, M. Dencheva-Zarkova, D. Yankov, and J. Genova, “Nanofiltration as a Sustainable Tool for Concentrating Bioactive Compounds in Mavrud Red Wine”, C. R. Acad. Bulg. Sci., vol. 79, no. 4, pp. 429–437, Apr. 2026.

Issue

Section

Chemistry